Excipients: butanol, potassium hydroxide, water d / i.
Packaged in 20 and 100 ml in glass bottles of appropriate capacity, sealed with rubber stoppers, reinforced with aluminum caps.
Registration certificate 77-3-18.12-0947 No. PVR-3-2.7 / 01959 of 08/31/12
Pharmacological (biological) properties and effects
Antibacterial drug of the fluoroquinolone group. The mechanism of the bactericidal action of enrofloxacin is based on the ability to inhibit the activity of the gyrase enzyme, which provides for DNA replication in a bacterial cell.
Enrofloxacin active againstgram-positive and gram-negative bacteria of the following species: Esherichia coli, Haemophilus spp., Klebsiella spp., Pasteurella spp., Pseudomonas spp., Proteus spp., Bordetella spp., Brucella spp., Chlamydia spp., Enterobacter spp., Campylobacter spp., Etihe spp., Chlamydia spp., Enterobacter spp., Campylobacter spp., Eupee spp., Chlamydia spp., Enterobacter spp., Campylobacter spp., Eryste. Corynebacterium spp., Staphylococcus spp., Streptococcus spp., Actinobacillus spp., Clostridium spp., Bacteroides spp., Fusobacterium spp., And Mycoplasma spp.
When i / m administration, enrofloxacin is rapidly absorbed into the blood and penetrates into almost all organs and tissues, reaching a maximum concentration within 0.5–1 h after administration. After a single injection, the therapeutic concentration of enrofloxacin is retained in the body for 24 hours. Enrofloxacin is eliminated from the body mostly unchanged and partially as a metabolite, ciprofloxacin, mainly with urine.
Enromag ® by degree of impact on the body belongs to the moderately hazardous substances (3 hazard class GOST 12.1.007-76).
The drug is administered to all types of animals s / c (pigs / m) 1 time / day for 3-5 days in the doses indicated in the table.
* - for the listed types of animals it is not recommended to use 10% solution.
Sows at metritis-mastitis-agalactia syndrome the drug is administered within 1-2 days.
In connection with a possible pain reaction, large animals should not be injected into one place more than 5 ml, small animals more than 2.5 ml of the drug.
Features of the drug at its first use and cancellation was not detected.
Avoid skipping the next dose of the drug, because this may lead to reduced therapeutic efficacy. In case of missing a single dose, the use of the drug is resumed as soon as possible in the same dose and according to the same scheme.
Contraindications to the use of the drug ENROMAG ®
- milking animals, due to the release of enrofloxacin with milk,
- with significant violations of the development of cartilage tissue,
- with lesions of the nervous system, accompanied by convulsions,
- puppies and kittens until the end of their growth period,
- females during pregnancy and lactation,
- with increased individual sensitivity of the animal to fluoroquinolones (including in history).
Special instructions and measures for personal prevention
In case of occurrence of allergic reactions, the use of the drug is stopped and antihistaminic and symptomatic drugs are prescribed to the animal.
Enromag® should not be used simultaneously with chloramphenicol, macrolide antibiotics, theophylline and NSAIDs.
Slaughter of pigs, cattle and small ruminants for meat is allowed no earlier than 14 days after the last injection of the drug. Meat of animals, forced killed before the expiration of the specified period, can be used after heat treatment for feeding fur-bearing animals.
Personal preventive measures
During the work with the preparation Enromag ® it is necessary to follow the general rules of personal hygiene and safety measures provided during the work with medicines. At the end of the work hands should be washed with warm water and soap.
In case of accidental contact of the drug with the skin or mucous membranes of the eye, they should be washed with plenty of water. People with hypersensitivity to the drug should avoid direct contact with Enromag ®. In the event of an allergic reaction or in case of accidental ingestion of the drug in the human body, you should immediately contact a medical institution (you should have the instructions for use of the drug or a label with you).
Empty vials from the drug should not be used for domestic purposes, they must be disposed of with household waste.
Enromag ® storage conditions
The preparation should be stored in the sealed packaging of the manufacturer in a dry, protected from direct sunlight, out of the reach of children, separately from food and feed, at a temperature of 5 ° C to 25 ° C.
Dispose of unused medication in accordance with the requirements of the legislation.
Composition and release form
Antibacterial drug for oral administration, which is an aqueous solution of enrofloxacin. 1 ml of the drug contains 100 mg of enrofloxacin base. It is a clear liquid from light yellow to yellow. Produced in the form of a 10% solution packaged in 1000 ml vials.
Enrofloxacin, which is part of the drug belongs to the group of fluoroquinolones. The mechanism of action of enrofloxacin is based on the ability to inhibit the activity of the enzyme gyrase, which provides for DNA replication in a bacterial cell. A microbial cell acts bactericidal. Active against Gram-positive and Gram-Noir Corina, and also mycoplasmas. With oral administration, enrofloxacin is well absorbed from the gastrointestinal tract, quickly enters the blood and penetrates almost all organs and tissues, reaching a maximum concentration in 1.5 - 2 hours after application, and remains in therapeutic concentration for 24 hours. Enrofloxacin is partially metabolized to ciprofloxacin and excreted mainly from the body with urine.
For the treatment of respiratory diseases, colibacteriosis, salmonellosis, pasteurellosis, necrotizing enteritis, hemophilia, mycoplasmosis, campylobacterium hepatitis, infections caused by Pseudomonas aeruginosa, Staphylococcus, as well as mixed infections and secondary infections in case of viral diseases, people who are looking for them, they are looking for them, they are looking for them, they are looking for them, they are looking for them. , lambs and piglets whose pathogens are sensitive to enrofloxacin.
Indications for use and mechanism of action
Used in the form of subcutaneous injections. Enrofloxacin after administration is rapidly absorbed into the blood and distributed throughout the body, getting into all organs and tissues. The maximum concentration of the substance is achieved within 1 hour after administration.
Enromag is available as an injection.
Assigned to animals for the following diseases:
- infection with E. coli,
- hemophilic bacteriosis,
- atrophic rhinitis,
- enzootic pneumonia,
- mastitis metritis-agalaty syndrome
- secondary bacterial infections,
- and other gram-positive and gram-negative bacteria.
The bactericidal action of enromag is based on the fact that enrofloxacin disrupts the synthesis of bacterial DNA, which leads to their death.
Dosage and method of use in veterinary medicine
For pets and birds means is injected subcutaneously 1 time per day. The course of treatment is on average from three to five days. The dosage is determined by the veterinarian on the basis of the body weight of the animal and the specific disease.
The dosage is calculated based on the weight of the animal.
Independent and uncontrolled use of it is unacceptable. On the basis of clinical data and laboratory tests, the veterinarian will prescribe an effective dosage and the necessary course of treatment, which will have to be completed completely.
It is impossible to cancel the enromagus to skip the injections and early The therapeutic effect in this case will be reduced, and the microorganisms may develop resistance to the drug. That will lead to a complication of the disease and the subsequent difficulty in treating the animal.
For example, 1 day - at the withers, the second in the area of the scapula, the third - in the area of the other scapula. If necessary, the introduction of the drug at a time in a volume greater than two ml for large animals and 1.5 ml for small ones, the dose should be divided into equal parts and pricked in different places on the body.
Side effects of the drug occur when exceeding the dosage and ignoring contraindications for admission.
Adverse reactions include:
Vomiting is one of the side effects of enromagus.
- loss of appetite
- negative impact on the development of cartilage tissue
- allergic reactions.
With long-term use of the drug is possible manifestation of dysbiosis.
In the event of adverse symptoms, it is necessary to consult a veterinarian for the appointment of a different drug therapy.
Contraindications for animals
Contraindications for admission is:
- individual intolerance of a pet to fluoroquinolones,
- lactation period
- gestation period
- the age of animals up to the year of small (cats, dogs, etc.), up to 1.5 years of large breed dogs,
- cartilage diseases,
- damage to the nervous system.
Storage conditions and shelf life
In a closed package in a dark place at room temperature is stored up to 3 years. After opening the bottle is not subject to storage.
Baytril - one of the analogues enromaga
Price and analogues
Enromag 10% 100ml - 250 rubles.
Enromag 5% 20ml - 100 rubles.
Enromag 5% 100ml - 180 rubles.
Enromaga analogues: Baytril, Enroksil, Enrosept, Enrofloks, Enrofloksatsin.
In the article I told about the preparation Enromag, its mechanism of action and indications for use.
Enromag is a yellowish injectable solution. The basis of the drug - the active ingredient enrofloxacin. The release form Enromaga - bottles of 20, 200 ml. Depending on the concentration of the drug contains in 1 ml of 50 or 100 mg of the active substance.
Means used in veterinary practice should be stored in sealed packaging, separately from food, at temperatures up to 25 ° C. After opening the bottle, according to the instructions for use, Enromag is not subject to storage: it must be fully used. A drug belonging to the fluoroquinol group is active against many bacteria, including staphylococci, streptococci, mycoplasma, clostridia.
When intramuscular injection is absorbed into the blood, reaching a maximum concentration within 1 hour after administration. Penetrates all tissues, organs of the animal. Therapeutic dose is usually maintained for 24 hours. Enromag is derived from the body of animals mainly with urine. When allergic reactions occur, Enromag is canceled.
To whom and when to appoint
Veterinarians use this drug in the treatment of cattle, various poultry, pigs, rabbits, as well as cats. Ernomag use, given the instructions for use, with:
In pigs, a veterinary medicinal product is used for atrophic rhinitis, symptoms of mastitis-agalactia, enzootic pneumonia.
Attention! Do not prescribe milking animals: clinical studies have shown the release of the drug with milk.
Enromag may not be prescribed for various disorders in the structure of cartilage tissue, for pathologies of the nervous system, aggravated by convulsions. Not recommended appointment kittens, puppies, until the period of growth ends.
The main nuances of use
When calculating the dosage of Enromag, you should strictly follow the instructions for use. Cattle horned animals are injected intramuscularly. The dose of the ernomag is calculated based on the weight of the sick animal. Pigs drug is administered subcutaneously. For rabbits, dogs, cats use 5% injection solution. Enromag is prescribed 1 time per day, the duration of application is 3-5 days. Using a veterinary agent, you should adhere to safety: the drug belongs to toxic substances (hazard class - 3).
With an overdose of Enromag, most animals have various symptoms: diarrhea, gagging, loss of appetite, depression of motor reactions. When treating poultry, the antibiotic is mixed with drinking water. The solution is prepared by calculating the concentration of 5 ml of the drug per 10 liters of liquid. The resulting drink is prescribed to birds for 5 days. Slaughter of animals is allowed for earlier than 14 days after the last administration of an ernomaga. Otherwise, the meat is subject to heat treatment, after which it is fed to fur-bearing animals.
The use of Enromag in veterinary medicine can successfully treat animal diseases caused by many pathogenic microorganisms.
What diseases of birds can be an indication for the use of Enromag
- bacterial diseases treatable with fluoroquinolones.
- Enteritis (necrotic type).
Manufacturers produce this veterinary preparation in two variations:
- oral administration
- for internal absorption.
Oral administration involves the preparation of a therapeutic composition at the rate of 5 ml Enromag diluted in 10 liters of water (10%, where 1 ml of the substance contains 100 mg of enroafloxacin).
Internal use implies the addition of the drug to the feed, based on 1 kg of feed / 100 ml Enromag.
In diluted form the drug retains its effect for 24 hours. Therefore, a fresh solution should be prepared every day. Duration of treatment should be at least 3 days.
The use of antibacterial drug for chickens
Growing stockings is not an easy task associated with providing appropriate pet care. Due to its young age, the chicks have a weak immunity, because of which they can suffer from infectious, viral and bacterial diseases. Since most diseases are infectious, in order to save the young it is necessary to start treatment in a short time. Among the list of diseases that can lead to death, it is worth highlighting Mycoplasmosis, Salmonellosis, Colibacteriosis. These diseases can be managed with Enromagus. After treatment This drug is recommended to drink chickens with vitamins.
Depending on the established diagnosis, the course of treatment with Enromagom can be extended from 3 days to 5 days. An example of this is the treatment of salmonellosis in birds.
After the solution with the drug enters the body of the chick or adult bird, the active substance can be detected in the organs and tissues of the body after 1.5 hours at the highest concentration. It is stored in the tissues of the bird for 24 hours, and Enromag is excreted from the body of the feathery through the urinary system.
This drug There are recommendations that should be taken into account. For example, the fact that Enromag should not treat a bird in parallel with steroids and chloramphenicol.
Enromag use in broiler chickens
Chickens of a broiler have protective properties of an organism even weaker, than usual breeds of domestic hens. A common disease of broilers is streptocosis, colibacteriosis and mycoplasmosis. In the first days of life, chickens should receive a special fortified feed that will strengthen the immune system.
However, such measures most often It becomes insufficient, and farmers who are engaged in the cultivation of this species of birds, begin to disappear the first 3-5 days with an antibiotic. Such a drug is, for example, Enromox, which can serve as both a medicinal and a prophylactic agent. If chickens are affected by salmonellosis, Komi infection, Pasteurellosis and respiratory diseases, Enromox can give a flock of birds that is given in a drinking solution (1l. Of water / 1 gram) in a course of 3-5 days.
An infection can be prescribed Enromag.
If the poultry farmer purchased the drug (10%) for oral use, then it is prepared according to the 5 ml / 10 l scheme. water. The course of treatment of broiler chickens stacked in 1 day.
When applying the second pharmacological type of veterinary medicine, the amount of water is significantly reduced, and the scheme looks like this: 5 ml Enromaga / 1l. water. The course of treatment also lasts 1 day.
In general, the treatment scheme for chickens and adult birds is no different. Only a course of treatment can be extended, as with the disease on Salmonellosis, it is 5 days.
Available contraindications to receive veterinary drugs
Contraindications to the use may be a detected allergic reaction to the drug. It is also not recommended to treat Enromag hens. This is due to the factthat substances from the drug can get into the egg. When the need arises to take the medicine, the egg should not be eaten by people.
For the entire course of therapy and after another 11 days, there is a taboo on the slaughter of this bird for the same reason.
During the treatment of poultry Enromag cannot be given parallel to the feathery Theofillin, Tetracycline, Chloramphenicol anti-inflammatory and nonsteroidal agents.
During the course of treatment with this drug, birds should not be given any other water, except for the prepared solution, which should be enough for all livestock within 24 hours.
Do not be afraid of overdose Enromaga at observance of the norms specified in the instruction, the calculated dose for a bird is 40 times lower than the limiting one.