Milbemaks and Praziquantel for cats and dogs


In the article I will tell about the preparation of milbemaks from worms, for what purposes it is used and how it works. I will give the recommended dosage, how much and instructions for use. I will list the contraindications for admission in dogs, the storage conditions of the drug, expiration dates, price and analogues.

Milbemaks - a veterinary drug designed for deworming animals.

Release form and composition of the drug milbemaks for dogs

Milbemaks is available in the form of tablets for puppies and small or adult dogs. There are also for cats. Anthelmintic tablets differ in the concentration of active substances.

For puppies and small breeds, the composition of 1 tablet:

  • 2.5 mg milbemycin oxime,
  • 25 mg of praziquantel.

For medium and large breeds, 1 tablet contains:

  • 12.5 mg milbemycin oxime,
  • 125 mg of praziquantel.
Pharmacology produces Milbemaks, which is packaged in 2 pieces in a blister.

Indications for use milbemax

Milbemax is assigned to pets for the treatment of invasions by nematodes, cestodes, ascaris, whipworms, tapeworms.

Diseases of pets endoparasites, adversely affect their health and health. Infection affects tissues, organs and body systems. In severe advanced forms, in the absence of treatment, death is possible. In case of confirmation of invasion, it is necessary to take a pet.

Antiparasitic agents are toxic. In the case of improperly selected dosage or anthelmintic drugs, can harm the health of the pet.

In treatment with an agent, the active components of milbemax disrupt the work of the nervous system of ectoparasites. These changes lead to paralysis of worms and their subsequent death.

After oral administration of the tablet, the active ingredients are quickly and almost completely absorbed.

After taking the pill, the drug is quickly absorbed in the intestine and within three days has a devastating effect on the parasites in all organs and tissues, then leaves the body through the excretory system. After applying the medication, the worms begin to be excreted from the body of the pet on the second day.

Before vaccination by age should not take the drug. Many vaccines just cause a significant increase in body temperature and even allergic reactions.

Giving laxative in such cases is strictly prohibited! You should contact your veterinarian as soon as possible.

Instructions for use anthelmintic tablets

The manufacturer recommends preventive deworming of dogs every three months. This event is a single dose of 1 dose of milbemax based on the weight of the animal. The same drug can be administered two weeks before vaccination and before viscous in the same dosage.

For the treatment of endoparasites, the medicine is given once during the feeding. The tablet must be mixed with food or hidden in a piece of meat. If the animal refuses to take it, it is necessary to crush the pill, mix it with water, pour the resulting suspension into the dog's mouth and squeeze it with the hand until the medicine is completely swallowed.

Treatment with milbemax in such cases is recommended for the purpose of a veterinarian, under supervision.

With a body weight of 25 to 50 kg, a double dose is given. With a weight of 50 to 75 kg - triple.

In the case of severe invasions, it is possible to re-use the drug as prescribed by a veterinarian.

Instructions for use of the drug milbemaks for dogs

Side effects

In rare cases, disorders of the digestive tract may manifest themselves in the form of diarrhea, vomiting, excessive salivation, and an increase in appetite.

In the event of the following symptoms in the dog after taking the drug, it is urgent to contact the veterinarian:

  • lethargy,
  • shiver,
  • convulsions
  • pallor of mucous membranes,
  • refusal to eat
  • strong salivation,
  • no stool for two days.
The instruction on milbemaks for dogs, claims that the pills are safe for all dogs

Contraindications for admission

Milbemaks is not recommended for use in collie, bobtail and sheltie dogs. These rocks are sensitive to the active substances of the drug. If necessary, the use of the drug on these dogs, you must consult with a veterinarian.

Milbemaks can not be used on exhausted dogs and puppies up to two weeks of age.

Price and analogues

The cost of the drug for puppies is approximately 500 rubles for 2 tablets. For adult dogs 350 rubles.

Similar antiparasitic drugs:

  • Drontal plus
  • Tsestal plus
  • Febtal combo
  • Canquantel
  • Milprazon
  • Troncil
  • Pratel
  • Dosalid
Drontal Plus

In the article I told about the veterinary drug milbemaks, in which cases it is used and how it works. Led the recommended dosage and method of administration. Listed contraindications for use, storage conditions, shelf life, price and analogues.

Milbemax / Praziquantel for Dogs and Cats

Milbemaks, Praziquantel are used to treat nematodes, ascaris, claws and tapeworms in dogs and cats. The drug is very effective in preventing infection with heartworms. Veterinarians also use milbemax for treating demodectic scabies.

Milbemaks is one of the drugs that is effective for the destruction of microfilariae.

Precautions and side effects

  • Although, in general, the drug is safe and effective in the dosage prescribed by a veterinarian, milbemax can cause side effects in some animals.
  • Milbemax / Praziquantel should not be used in animals with known hypersensitivity or allergy to the drug.
  • The drug should not be used for puppies under the age of 2 weeks and kittens under 6 weeks. This also applies to animals with low birth weight less than 500 g.
  • The most common side effects are drooling, lethargy, decreased coordination.
  • There are several unconfirmed reports of convulsions and other disorders of the central nervous system after milbemax administration.
  • After applying milbemaks in order to destroy the heartworm, the dog should be carefully monitored for shock reactions. If the animal has shock, then it must be hospitalized for maintenance therapy.

How to apply milbemaks

Milbemaks is available in two versions: for cats and dogs.

For dogs:

  • Milbemaks for adult dogs containing 12.5 mg milbemycin oxime and 125 mg praziquantel.
  • Milbemaks for small dogs and puppies, containing 2.5 mg milbemycin oxime and 25 mg praziquantel.

For cats:

  • Milbemaks for cats containing 16 mg milbemycin oxime and 40 mg praziquantel.
  • Milbemaks for small cats and kittens containing 4 mg milbemycin oxime and 10 mg prazikantel.

Milbemaks dosage for dogs and cats

  • The drug can not be used without consulting a veterinarian.
  • It is recommended to give milbemaks with food.

For dogs:

  • Dosage for dogs weighing 0.5 to 1 kg is 1/2 a milbemax tablet for small dogs and puppies.
  • Dosage for dogs weighing from 1 to 5 kg is 1 milbemax pill for small dogs and puppies.
  • The dosage for dogs weighing from 5 to 10 kg is 1/2 tablet of milbemax for adult dogs.
  • Dosage for dogs weighing from 10 to 25 kg is 1 milbemax tablet for adult dogs.
  • Dosage for dogs weighing 25 to 50 kg or more is 2 milbemax tablets for adult dogs.

For cats:

  • Dosage for small cats and kittens weighing 0.5 kg to 1 kg is 1/2 a milbemax tablet for small cats and kittens.
  • Dosage for cats weighing 1 kg up to 2 kg is 1 milbemax pill for small cats and kittens.
  • Dosage for cats weighing 2 kg to 4 kg is 1/2 tablet of milbemax for adult cats.
  • Dosage for cats weighing 4 kg to 8 kg is 1 milbemax tablet for adult cats.

Make sure you use the product according to the instructions for use and according to the instructions of the veterinarian. Even if your pet is better, he must undergo a full course of treatment to prevent re-infection. A monthly dosage is usually recommended for the prevention of heartworm (filarias).

Release form, composition and packaging

Tablets for oral administration (for puppies and small dogs) white, oval-shaped, with an "AA" imprint on one side and an "NA" imprint on the other side, with a fault line on both sides.

Excipients: microcrystalline cellulose, sodium croscarmellose, povidone, lactose monohydrate, colloidal silicon, magnesium stearate.

2 tablets are packaged in blisters of aluminum foil, placed in 1 or 2 pcs. in a carton box.

Registration certificate 826-3-13.13-3137 No. PVI-3-7.7 / 02354 of 04/12/16

Pharmacological (biological) properties and effects

Combined antihelminthic drug.

Milbemycin Oximewhich is a part of the preparation, belongs to the group of macrocyclic lactones secreted as a result of enzymatic activity of Streptomyces hygroscopicus var. Aureolacrimosus. Active against larvae and imago nematode, parasites in the digestive tract of dogs and cats, and nematode larvae Dirofilaria immitis.

The mechanism of action of milbemycin is due to increased permeability of cell membranes to chlorine ions, which leads to overpolarization of the cell membranes of the nervous and muscular tissue, paralysis and death of the parasite. After oral administration, the maximum concentration of milbemycin oxime in the blood plasma of cats is reached after 2 hours, in the blood plasma of dogs within 2-4 hours. The compound is excreted from the body mainly unchanged.

Praziquantel is an acylated pyrazinisoquinoline derivative, active against cestodes and nematodes. Increasing the permeability of the cell membranes of the parasite for calcium ions, causes depolarization of the membranes, muscle contraction and destruction of the tegument, which leads to the death of the parasite and contributes to its removal from the body of the animal. After oral administration of the drug, the maximum concentration of praziquantel in the blood plasma of cats is reached after 1 hour, in the blood plasma of dogs - after 1-4 hours. The compound is excreted mainly as inactive metabolites in the urine, the half-life in cats is about 3 hours, Praziquantel is excreted within 2 days.

According to the degree of impact on the body, Milbemaks® tablets for cats belong to moderately hazardous substances (hazard class 3 according to GOST 12.1.007-76), in recommended doses does not have sensitizing, embryotoxic and teratogenic effects, in different doses and cats are well tolerated . The drug is toxic to fish and other aquatic organisms.

Milbemaks ® tablets for dogs according to the degree of impact on the body belong to moderately hazardous substances (hazard class 3 according to GOST 12.1.007-76), in recommended doses they do not have sensitizing, embryotoxic and teratogenic effects. The drug is toxic to fish and other aquatic organisms.

Indications for use of the drug MILBEMAX ®

Cats for treatment and prevention:

- cestodosis caused by helminths of the species Dipylidium caninum, Taenia spp., Echinococcus multilocularis,

- nematodoses caused by helminths of the species Ancylostoma tubaeforme, Toxocara cati, Dirofilaria immitis (prevention of the disease for 1 month),

- mixed nematode-cestodosis invasions.

For dogs for treatment and prevention:

- cestodosis caused by helminths of the species Dipylidium caninum, Taenia spp., Echinococcus spp., Mesocestoides spp.,

- nematodosiss caused by helminth species Ancylostoma caninum, Toxocara canis, Toxascaris leonina, Trichuris vulpis, Thelazia callipaeda, Angiostrongylus vasorum (reduces the intensity of the infection), Crenosoma vulpis (reduces the intensity of the infection), Dirofilaria immitis (disease prevention)

- mixed nematode-cestodosis invasions.

Application procedure

Milbemaks® tablets for cats

The drug is used for cats once during feeding with a small amount of food or forcibly administered to the root of the tongue after feeding at the minimum therapeutic dose of 2 mg of milbemycin oxime and 5 mg of praziquantel per 1 kg of animal weight, based on:

Prescription drug

Even the most well-groomed pets, including cats, are in the so-called risk zone and easily pick up a variety of intestinal parasites.. A significant part of the cat helminths is classified as dangerous for humans, and is transmitted to people in the process of close contact with the four-legged pet. Extreme care should be exercised by families with children.

Symptoms of helminthic invasion in a cat include:

  • passive, depressed state,
  • a complete rejection of food or, on the contrary, pronounced activation of appetite,
  • a perversion of appetite and attempts to eat inedible objects or earth,
  • dull coat,
  • hair loss
  • crusts in the corners of the eyes,
  • digestive disorders with diarrhea, vomiting or constipation,
  • blood in the feces
  • signs of intestinal obstruction,
  • rapid weight loss
  • barrel-shaped abdominal distention,
  • lowering immunity
  • uncharacteristic pallor of mucous membranes,
  • lag in growth of puppies and kittens,
  • convulsions as a result of general intoxication of the body with the products of the vital activity of helminths
  • worms in feces.

A pet's intestine can become a haven for roundworms and tapeworms, as well as flukes and Giardia.. Veterinary drug "Milbemaks" is prescribed for treatment and prophylactic purposes, shows high efficiency and prevents the development of various helminthic invasions in animals.

It is interesting! In order not to deprive oneself and all family members of the pleasure of communicating with a pet, it is sufficient to take a responsible approach to the treatment and prevention of helminthic invasions, using for this purpose the broad-spectrum drug Milbemaks.

Composition, release form

Means "Milbemaks" is a combined modern de-worming drug, eliminating in the body the four-legged pet of intestinal parasites. The basic substance of this drug is represented by milbemycin oxime, which simultaneously belongs to the group of antihelminthics and antibiotics.

This substance can effectively affect nematodes that inhabit the gastrointestinal tract of a pet and enter the bloodstream, as well as the liver, lungs and kidneys. "Milbemycin" easily enters the blood plasma and affects the larval stage of parasites for several hours, after which it is eliminated completely from the body of the animal.

It is interesting! Auxiliary components of the veterinary drug "Milbemaks" do not have any therapeutic effect, but the beef flavoring contained in the composition helps to feed antihelminth tablets to a pet.

Praziquantel, a component of the veterinary medicine, infects nematodes and cestodes, effectively acting on the helminth cell membranes. Dead parasites are digested, after which they naturally leave the pet. The peak concentration of this component in the blood plasma is observed 1-4 hours after using the drug, and then the substance is biotransformed in the liver tissues. The active component of praziquantel is completely excreted from the cat’s body along with urine in just a couple of days.

Instructions for use

The instructions supplied by the manufacturer to the veterinary anthelmintic drug "Milbemaks" are very simple and intuitive. In the morning, when feeding, you must feed your pet a drug, the amount of which corresponds to the weight of the pet. Pink tablets are fed to kittens and young animals, and red tablets are produced for adult pets.

On the elongated tablets with beveled edges in the central part there are prints of "NA" and "BC", as well as risk. "Milbemaks" is given to cats once in the morning feeding, or is forcibly introduced directly to the root of the animal's tongue after eating a therapeutic minimum dose.

When to apply Milbemaks?

Pets, however well groomed, are at risk. It is easy for them to catch intestinal parasites. Dense communication of people with animals can have unpleasant consequences - most of the worms are dangerous to humans. Increased caution should be shown to families with children.

In the intestines of animals find shelter round and tapeworms, flukes, Giardia. More than a third of all known worms are dangerous to humans.

What to do? Really it is necessary to refuse pleasure of close contact with four-legged friends? Of course not - it is enough to approach responsibly the issue of the prevention and treatment of worm infestations in them.

Pharmacological properties of the drug

Milbemaks is a combined deworming drug that effectively eliminates intestinal parasites of various species in animals.

The basic substance of the drug for worms, milbemycin oxime, belongs simultaneously to the group of antibiotics and antihelmintics. Вещество результативно поражает нематод — паразитов, населяющих ЖКТ домашних питомцев.

Гельминты обосновываются в ЖКТ животных, но личинки имеют свойство проникать и в кровь, и в жизненно важные органы: лёгкие. печень, почки. Мильбемицин способен проникать в плазму крови и воздействовать на личинки паразитов на протяжении нескольких часов. After a time, the active substance is completely excreted from the body.

Praziquantel infects cestodes and nematodes. By acting on the cell membranes of parasites and their depolarization, the effect of destruction of flatworms is achieved. They die, are digested and leave the body of the animal. The peak concentration of a substance in the blood plasma occurs 1-4 hours after taking the pill, then it is mobile and effectively biotransformed in the liver. Out of the body with urine for 2 days.

It should be remembered that Milbemaks moderately hazardous substance, belongs to the III class of danger. The drug is poisonous for aquarium fish, crustaceans and a number of other organisms adapted for life in water. The drug should be applied strictly dosed to not harm the animal.

Composition and release form

Milbemaks is available in several versions:

  • for puppies and small dogs, tablets of elongated form in a white shell with a transverse risk are offered. On the one hand, you can find a print of "AA" and "NA".
  • For kittens and young cats, a tablet form preparation in a beige-brown casing is proposed. The shape is elongated with beveled edges. In the middle there is a risk and imprints "BC" and "NA".
  • for dogs.
  • for cats. The active ingredients of the drug are milbemycin and praziquantel. The drug goes on sale, packaged in 2, 4, 10 tablets in one standard, and packs of up to one hundred tablets in a blister are offered for dogs. Blisters are packed in cardboard boxes with the image of an animal for which the drug is intended in a given dosage.

Symptoms of helminth infection in animals:

  • passive, depressed state,
  • complete rejection of food, or vice versa increased appetite,
  • distortion of appetite (attempt to eat objects unfit for this, land),
  • dull coat
  • hair loss
  • crusts in the corners of the eyes,
  • violation of digestion (diarrhea, vomiting, constipation),
  • blood in the feces
  • signs of intestinal obstruction,
  • rapid weight loss
  • barrel abdominal distension,
  • reduced immunity
  • pallor of mucous membranes,
  • lag in growth of puppies and kittens,
  • convulsions, as a result of general intoxication as a result of the vital activity of helminths,
  • sometimes in the feces you can see thin "worms".

When should you not use Milbemaks?

Milbemaks is contraindicated in puppies for the following dog breeds:

The reason is the increased sensitivity of animals of these breeds to the components of the preparation.

It is not recommended to give the drug to puppies up to 2 weeks of age or animals weighing less than 0.5 kg. Milbemaks for dogs is intended for the treatment of animals weighing more than 5 kg.

Kittens up to 6 weeks, the drug also does not give. Milbemaks for young cats does not apply to animals whose weight does not reach half a kilo. Milbemaks for cats is designed for animals weighing from 2 kg.

Dosage and rules of administration

Anthelmintic agent is used once. Oral, with food. Reception should be monitored, as some animals refuse to take medicine voluntarily. In these cases, you must put the pill on the root of the tongue and squeeze the pet with your hands until the medicine is swallowed.

To avoid poisoning the animal, you should carefully consider the dosage of the drug.


The defeat of dogs with angiostronglosis requires 4 times the drug at weekly intervals.

In order to prevent dirofilariasis (in disadvantaged regions), Milbemax is taken in the warm season in places with the appearance of vectors of infection (blood-sucking insects). Once with the appearance of insects, and then with a monthly frequency. Last application one month after the disappearance of mosquitoes and mosquitoes. Prevention of dirofilariasis requires consultation and observation of a specialist in order to eliminate the presence of microfilariae in the animal’s blood.

Nuances of personal hygiene

When giving medicine to an animal, it is necessary to comply with a number of hygienic requirements:

  • At the time of introduction of Milbemaks, smoking, eating or drinking is contraindicated.
  • At the end of tactile contact with the medicine you need to wash your hands with soap and water.
  • If the drug was mistakenly used by a person, you need to drink several glasses of warm water and seek medical help from a specialist. For effective assistance, you must show the label of the drug, which lists the substances included in its composition.
  • At the end of the shelf life of the drug, the package with unused pills can simply be thrown away. Special measures to eliminate the overdue Milbemaks not required.

Manufacturer and Price

Manufacturer Milbemaks - company NOVARTIS SANTE ANIMALE S.A.S. (France)

Price from 299 rubles. It can vary depending on the dosage and the number of tablets, as well as the region of implementation.

Drontal plus the price of 580-730 rub for 6 tablets,

Pratel - 310-350 rubles. for 10 tablets,

Cannavtel - 420 rub 6 tablets.

You can write your review about Milbemaks below!

Recently, I was bought a Scottish Fold kitten, and after a while he had worms! Milbemaks rescued us for kittens. Simple and effective tool. The kitten took a pill for food and instantly ate it straight from the hands! The veterinarian said that the tool will quickly relieve the baby of parasites, and, in the tray in the toilet, we will not find the "consequences of exposure" of the drug. Helminths are digested right in the stomach completely. So it turned out.