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Ivermek: dosage, overdose and instructions for use

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Injection transparent, opalescent, colorless or light yellow.

Excipients: dimethylacetamide, polyethylene glycol-660-hydroxystearate, benzyl alcohol, water d / i.

Packaged in 1, 10, 20, 50, 100, 200, 250, 400 and 500 ml in glass or plastic bottles of appropriate capacity, sealed with rubber stoppers, reinforced with aluminum caps.

Vials of the drug, packaged in 1 ml, labeled indicating the organization of the manufacturer, the name and volume of the drug, batch number, expiration date and packaged in 50 pieces in cardboard boxes with instructions for use.
Vials of the drug, packaged in 10 ml-500 ml, and cardboard packs are labeled with the name of the manufacturer, its address and trademark, name, purpose, method of use and the amount of the drug in the bottle, the name and content of active ingredients, the number of bottles in package, serial number, date of manufacture, expiration date, storage conditions, the labels “For animals”, “Sterilno”, state registration numbers, information on conformity assessment, TU designations and provide instructions for use.

Registration certificate number and registration date: TAC-2-1.2 / 00926 04/16/09

Pharmacological (biological) properties and effects

Antiparasitic drug. Ivermectin, which is part of the drug, enhances the production of neurotransmitter inhibition - gamma-aminobutyric acid, which leads to impaired transmission of nerve impulses, paralysis and death of the parasite.

It has a pronounced antiparasitic effect on the larval and sexually mature phases of the development of nematodes of the gastrointestinal tract and lungs, the larvae of subcutaneous, nasopharyngeal, gastric gadflies, lice, bloodsucker and sarcoptoid ticks.

After parenteral administration of the drug, ivermectin is rapidly absorbed from the injection site and distributed in the organs and tissues of the animal, providing a parasiticidal effect for 10-14 days. Excreted in the urine and bile, in lactating animals also with milk.

According to the degree of impact on the body, according to GOST 12.1.007-76, Ivermek belongs to moderately hazardous substances (hazard class 3), the active ingredient, ivermectin, belongs to extremely hazardous substances (hazard class 1). In recommended doses, the drug does not have an embryotoxic, teratogenic and mutagenic action, it is rapidly destroyed in the external environment.

Indications for use of the drug IVERMEC

With therapeutic and preventive purposes for arachno-entomozah and nematodoses:

- cattle with strongyloses, trichocephalosis, strongyloidosis, teliasiasis, sifunculoses, hypodermatosis, psoroptosis, sarcoptosis, and chorioptosis,

- to the sheep and the goat,

- deer with dictyocaulosis, ostertagiasis, nematodirosis, strongyloidosis, trichocephalosis, edemaenosis, cefenomyosis and sarcoptosis,

- camels with dictyocaulosis, ostertagia, nematodirosis, strongyloidosis, trichocephalosis and sarcoptosis,

- to pigs with trichocephalosis, ascariasis, metastrongylosis, esophagostamosis, strongyloidosis, stefanurosis, hematopinosis and sarcoptosis.

Application procedure

The drug is administered to animals in compliance with the rules of asepsis once a / m: pigs - in the neck or inner thigh, in other species - in the area of ​​the croup or neck in the following doses:

large and small cattle, deer and camels - 1 ml of Ivermek per 50 kg of animal mass (200 μg of ivermectin per 1 kg of mass),

pigs - 1 ml of Ivermek per 33 kg of animal mass (300 μg of ivermectin per 1 kg of mass).

AT severe casessarcoptoidosis the treatment is carried out twice with an interval of 8-10 days.

If the volume of the injected solution is more than 10 ml, it should be administered to the animal in several places.

The treatment of animals with nematodoses is carried out in the fall before staging on the stall maintenance and in the spring before taking out to pasture, against gadfly invasions - immediately after the end of the summer gadflies, against the arachno-entomoses pathogens - according to indications.

Each batch of drug is pre-tested on a small group (7-10 heads) of animals. In the absence of complications within 3 days proceed to the processing of the entire population.

Special instructions and measures for personal prevention

Slaughter of animals for meat is allowed not earlier than 28 days after the last injection of Ivermek. In the case of the forced slaughter of animals before the deadline, the meat can be used as feed for fur-bearing animals.

Personal preventive measures

When working with Ivermek, you should follow the rules of personal hygiene and safety in accordance with SanPiN 1.2.1077-01 "Hygienic requirements for the storage, use and transportation of pesticides and agrochemicals".

Empty vials from the preparation are neutralized by autoclaving (0.8 atm., 40 minutes) or by boiling for 1 hour. The areas of workplaces contaminated by the preparation are neutralized with 5% sodium hydroxide solution.

Veterinary Description

Ivermek - Veterinary Medicine, often used as a broad-spectrum anthelmintic drug. It also effectively fights deprivation and parasitic diseases caused by arthropods (arachnoentomoses).

The form of release of medicinal substance Ivermek - solution for injections. A milliliter of the working solution contains ten milligrams of the active ingredient - ivermectin. In addition, the solution contains forty milligrams of tocopherol acetate, known as vitamin E. The rest of the preparation is filled with auxiliary substances.

The solution for injection is almost transparent, with a barely perceptible specific odor. The substance is packaged in dark, glass containers (volume from 1 ml to 500 ml), sealed with rubber caps, which are additionally wrapped in a layer of aluminum. Capacities from 400 ml to 1 thousand ml are made of special plastic and corked with plastic covers.

The drug should be kept in the dark and cool, far from children, as indicated in its instructions for use. For animals Ivermek can be used for two years, provided that its vial is not compromised. It is worth noting that only forty-five days are given in order to use the opened bottle. Then the drug becomes unsuitable for further use.

This veterinary medicine is absolutely non-toxic if used strictly according to the instructions. It does not affect the development of embryos and very quickly resolves after the introduction into the muscle tissue of the animal.

The drug shows increased efficiency in the fight against nematodes and cystodes, parasitic on the tissues of the liver, lungs, gastrointestinal tract and heart. It destroys most of the known types of ectoparasites - ticks, fleas, lice, gadflies and mosquitoes.

The breakdown products of the drug are excreted by the kidneys and bile secretions. In females that feed their offspring, the substance is excreted along with the milk.

Method of application and indications for use

Ivermek is used for goats, camels, sheep, cattle, pigs, deer, as well as for horses. The Ivermek manual contains information that it should be used when helminths occur in animals that are localized in the gastrointestinal tract and lungs, as well as in cases of such diseases as:

  • trichocephalosis,
  • cestodes,
  • esophagostomosis,
  • strongyloidiasis
  • toksokaroz,
  • nematodoses,
  • scabies,
  • ascariasis

Good results can be achieved when applying Ivermeka from worms in young farm animals: calves, pigs, foals. The drug is also effective in mallophagosis, psoroptosis, lice, demodicosis, colitis and subcutaneous or nasopharyngeal gadfly. Young poultry (chickens, goslings, ducklings and turkey poults) are prescribed for the treatment of entomoses caused by Deriatorktes mutans, Ceratophyllus gallinae and Aphaniptera spp.

The drug is injected only once during the prophylactic or therapeutic season, by intramuscular injection:

  • Cats and dogs injections put in the muscle between the shoulder blades or withers.
  • For an adult pig or piglet suffering from colitis, the substance is injected into the thigh muscle - inside the thigh, as well as into the muscles of the neck.
  • Other animals are advised to inject into the neck or croup.

The following dosages of Ivermek are recommended:

  • Cats, rabbits and dogs should receive a milliliter of the drug per 5 kg of body weight.
  • Pigs and piglets can get a milliliter of substance per 33 kg of its mass.
  • Horses, cattle and small cattle (sheep, goats) should receive a milliliter of medicine for every 50 kg of body weight.

The dose of a substance of ten milliliters for better resorption must be entered in different places of the body, because this dose is considered to be quite large.

Agricultural animals should be injected before determining their wintering (stall period), as well as before the beginning of the pasture season.

For the prevention of bloodsucking larvae (gadfly) larvae, the medicine is used immediately after the summer. Against arachnoentomozov or ectoparasites drug is used as needed - during the entire period of activity of the parasites.

The drug can be administered twice only in severe cases of defeat worms. Then injections are done at intervals of seven to ten days.

Contraindications

Like all veterinary or medical drugs, Ivermek has a hazard class. It belongs to the category of moderately dangerous veterinary drugs.

An adverse reaction to this medicine can give animals that have some sensitivity to the active substance or to its other components.

The drug is categorically contraindicated in the following categories of animals:

  • females awaiting offspring,
  • weak or malnourished individuals (for example, those who have just been ill),
  • sick animals.

If, after an injection, an animal develops depression, gastrointestinal upset, lack of appetite or allergies, this is a manifestation of hypersensitivity to the drug. This condition is usually not dangerous for him and passes spontaneously within two to three days. In addition, there may be a slight increase in temperature in young animals, for example, in calves. Sheep can react to the drug by frequent urination, depression, and disruption of the gastrointestinal tract.

If the condition of the animal does not improve within three days after the injection, these are signs of a possible overdose. There is no special detoxification agent for Ivermek, therefore symptomatic therapy is carried out, and the drug is later replaced with a similar one. For example, you can use Ivermezole, Ivermin, Ivermepharm, Iverveksan or Iverlik. You can also use another similar drug containing ivermectin - Ivomek, instructions for use which is similar to the instructions for Ivermek. It is worth emphasizing that the choice of a similar drug should be the responsibility of the veterinarian.

If the farm is planned to be slaughtered, then it should be borne in mind that the meat of animals treated with Ivermek can only be eaten twenty-eight days after injection. This also applies to milk. If slaughter took place earlier, then the meat of dead animals is recommended to be fed to fur-bearing animals or sent for the production of meat and bone meal.

Means description

Ivermek's active ingredient is ivermectin. 1 ml of solution contains 10 mg of this drug. The second component is vitamin E. In the same volume its share is 40 mg. The rest is auxiliary components for better absorption and action of the drug.

Release ivermek only in the form of solution for injection. It is a translucent, slightly yellowish liquid. Packing - bottles and ampoules with a volume of 250, 100, 50, 20, 10, 1 ml. The container is hermetically sealed with rubber caps with tin clamps or aluminum caps. The largest capacity is half a liter with a plastic cover.

With ivermek treat pets and poultry. The active substance inhibits parasites that attack cows, sheep, goats and other domestic animals. The drug actually paralyzes the nervous system of parasites and immobilizes them: insects die and dry off the surface of the skin. Pest offspring are also hit. To get the full effect, you need to give ivermek to your pet for at least two weeks. Displays medication using the excretory system of the animal organism.

Attention! The advantage of the drug - in the speed of action. Ivermeka solution spreads through the circulatory system and muscle tissue in a matter of minutes.

Medicinal properties of the drug

Instructions for use limits the range of parasites with which ivermek fights:

  • scabies and lice,
  • helminthiasis in the intestines, lungs or stomach,
  • mallophagus,

  • nasopharyngeal or subcutaneous gadfly,
  • footrot,
  • eye nematode.

Instructions for use contains the following indications:

  1. The medicine is pricked by the bird's young during the molt. Means fights with entomozy and acarosis. Also, the instructions for use allow prophylactic injections in early spring.
  2. For dogs and cats, the drug helps with depriving.
  3. Calves, young and adult pigs ivermek prescribed for hematopinosis, trichocephalosis, esophagostomosis.

In the case of poultry, ivermek helps to get rid of the common red chicken mite and other specific parasites. The latter usually affect the entire chicken coop. Breeders do not have time to isolate the carrier of insects. Contaminated livestock becomes restless and reduces productivity. Pharmacologically contraindicated treatment with ivermec:

  • with infectious diseases of complex shape,
  • pregnant females (no later than 28 days before the start of feeding the pups),
  • chickens no later than 14 days before the start of egg-laying,
  • milk females whose milk is used for food.

Dosage and features of use

For different animals, instructions for use give the following recommendations:

  1. Bird injections do not. The drug is diluted in water and give with drink. Dose - 0.4 ml per 1 kg of mass. It is dissolved in a quarter of the daily water rate. With nematodes, ivermeca is taken once. With dermatosis - double with an interval of a day. The course is repeated after 2 weeks.
  2. Dosage for small cattle - 1 ml per 50 kg of weight. From worms make one shot. With lice, scabies and other skin diseases - two shots with an interval of 10 days. The injection is performed in the neck or thigh. The same dose and order of administration is used for rabbits and pigs.
  3. For cattle, dosage is similar. The injection site is croup or neck.

Council If the injection dose is more than 10 ml, then it must be administered in different places. For animals weighing less than 5 kg, dilute the product with any suitable solution.

Preventive treatment of animals is carried out in early spring and late autumn. Slaughter of poultry and eating its meat in food is permitted not earlier than 9 days after the use of the medicine. Ivermek store in a cool, dry and shaded place. Term in the closed state - 2 g, after opening the jar - 20 days.

pharmachologic effect

This medicine is classified as an anthelmintic, anti-parasitic drug that has a general effect.

The effectiveness of the active substance is due to its ability to affect the penetration of chlorine ions through the cell membranes of the nerve and muscle fibers of the parasite. This effect entails a violation of the nerve signals, resulting in paralysis and death of the parasite.

After intramuscular administration, the drug is rapidly absorbed, after which it is evenly distributed through the body tissues of the animal to provide a comprehensive antiparasitic effect.

Elimination of the drug occurs with urine and bile, and during lactation - and with milk.

Introduce the drug must be in accordance with the rules of asepsis, intramuscularly: pigs and piglets in the muscles of the neck or medial surface of the thigh. In addition, the solution is allowed and in the area of ​​the croup.

Ivermek for animals is effective in the following diseases:

There are a number of circumstances precluding the use of this drug:

  • The presence of an animal infectious disease.
  • Weakened condition.
  • Last third of pregnancy.
  • The use of Ivermek and other ivermectin derivatives in milking animals is unacceptable.

With great care should apply this tool in cats and dogs. Dogs of collie and sheltie breeds are particularly susceptible (when using this drug, they are likely to be fatal).

In case of intolerance to Ivermek, other drugs that have the same active ingredient (for example, Ivomek) cannot be used.

Individual hypersensitivity to ivermectin can lead to the following phenomena:

  • hypersalivation,
  • increased urination and bowel movements,
  • ataxia syndrome.

In most cases, the listed symptoms regress on their own, without requiring dosage adjustment or any specific treatment. В случае, если побочные реакции сохраняются в длительно, не регрессируя, необходимо обратиться за консультацией специалиста.

Во избежание развития негативных побочных эффектов настоятельно рекомендуется соблюдать все рекомендации, зафиксированные в инструкции по применению.

Молоко и мясо пролеченных Ивермеком животных не допускается для использования в пищевых целях ранее, чем через 28 суток после обработки (использование данных продуктов для кормления животных допускается).

Tanks from the solution should be neutralized by autoclaving or boiling.

Do not use the drug later than 42 days. after opening the bottle.

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The composition of the drug ivermek and release form

Ivermek - a drug whose action is aimed at the destruction of parasites in farm animals: pigs, piglets, sheep, calves and horses, dogs and cats. The main active ingredient is ivermectin.

Ivermek is issued packaged on 1, 10, 20, 50, 100, 200, 250, 400 and 500 ml in glass bottles

The drug is available in several forms:

  1. Injection solution. Odorless liquid with a yellowish tint. Available in sterile glass or plastic bottles, the volume of which can be 1, 10, 20, 50, 100, 200, 250, 400 and 500 ml.
  2. Solution for internal use with the prefix OR. It is used to treat birds. Liquid with a yellowish tint. Available in white plastic bottles with a capacity of 500 ml.
  3. Gel. The composition includes ivermectin, lidocaine and panthenol. Transparent gel, which may have a slightly yellowish color. Available in tubes or syringes of 2, 5, 10, 20, 30, 40 and 50 ml.
  4. Spray. Colorless, odorless liquid. Available in two types of bottles: equipped with spray nozzles (10, 30, 50 and 100 ml) or without them (20, 25, 50, 100, 125, 150, 200, 250, 300 and 350 ml).

The mechanism of action of the drug in veterinary medicine

Ivermectin, which is part of the drug, affects both external and internal parasites in dogs. These include worms (tape and round) and their nematodes, ticks (subcutaneous and scabies), lice and fleas.

Under the influence of ivermectin, the transmission of nerve impulses in the body of the parasite is disturbed, thereby paralyzing it, and then it dies.

Tapeworm

Indications for dogs and cats

Indications for use are as follows:

  • helminth infection (toxascaridosis, toxocarosis, ankilostomiasis, uncinaria, etc.),
  • sarcoptosis (itch mite),
  • otodectes (ear mite),
  • demodicosis (subcutaneous mite),
  • fleas and lice.

When applied topically (gel or spray) it has a soothing and anti-wake effect. Lidocaine relieves pain, and panthenol promotes faster healing of the affected skin.

Instructions for use and dosage

When infected with internal parasites use injectable form of the drug. The required dose (0.2 ml per 10 kg of body weight) is administered intramuscularly. The procedure is carried out once. It is acceptable to dilute with distilled water if the animal is small and it is difficult to calculate the exact dosage.

Instructions for use ivermeka for animals

With tick infestation, use gel or spray:

  1. Sarcoptosis and demodicosis. The crusts formed on the skin are soaked, and then a gel or spray is applied to the affected areas at a rate of 0.2 ml per kilogram of mass. Just spend 2-4 treatment at different intervals: gel - every 5-7 days, spray - in 3-5 days.
  2. Otodecosis. The affected ear is pre-cleaned from scabs, and then 0.5-2 ml of gel or 0.5-1 ml of spray is injected into each ear canal. Re-processing is carried out in 5-7 or 3-5 days, respectively. It is permissible to repeat the course until complete recovery.

Contraindications and side effects in animals

The tool is strictly contraindicated for pets of sheltie and collie breeds, as well as bobtail. These animals are especially sensitive to ivermectin. Injectable ivermek can be used to treat dogs no more than 2 times, between injections should take at least 10-14 days.

These symptoms go away on their own within 1-2 days.

Disruptions to the drug use regimen should be avoided.

Personal preventive measures and special instructions

Empty bottles must be processed by autoclaving or boiling for an hour. After this procedure, containers can be disposed of.

If during the treatment of the animal in the form of a solution, spray or gel got on the skin, it is washed off with warm soapy water. During pet processing, wear a gauze bandage, and latex or rubber gloves on your hands.

Storage rules and shelf life

The drug is stored in a dark and dry place at a temperature of from 0 to +25 degrees. The solution retains its properties for 2 years from the date of issue.

Ivermek should not be used simultaneously with drugs containing macrocyclic lactones

Cost and analogues

A bottle with a volume of 1 ml has a price of 40-60r., 20 ml - 120-140r., 50 ml - 180-210r., 100 ml - 350-380r., 500 ml - 1600-2000r. The average cost of spray 30 ml varies from 300 to 350 rub. A tube with a gel, with a volume of 10 ml, has a price of 150-180 rubles, 30 ml - 350-400 rubles.

Preparations with the active ingredient ivermectin are:

  • novomek,
  • iwomek
  • acaromectin,
  • iverslect
  • otodectin,
  • iversan
  • baimek,
  • alfamek.
Novomek 1% rr

Ivermek is a fairly toxic drug that effectively destroys external and internal parasites in farm animals, dogs and cats. During use, care must be taken. Used vials disposed of according to the instructions.

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