Ticks can trigger the development of piroplasmosis in domestic animals. To prevent such a disease, it is necessary to prevent the attack of ticks and other parasites on pets. To do this, apply various tools in the form of drops on withers, collars and sprays. One of the most effective is the drug "Frontline". The feedback on this tool is mostly positive. It is about him, our article.
The composition of the tool
The drug "Frontline" (the price of the drug depends on the volume of the pipette and is in the range of 220-400 rubles) is a drug insecticide-acaricide in the form of a colorless transparent solution with a specific odor exclusively for external use. The main active ingredients of the drug are S-methoprene - 8.8% and fipronil - 9.8%, auxiliary - polysorbate and polyvidone.
pharmachologic effect
The drug "Frontline Combo" (instructions for use will be described below) has a pronounced contact insecticoacaricidal effect. Active in the preimaginal and imaginal phases of development of lice, ticks, lashes, fleas, which can parasitize cats or dogs.
Under the action of fipronil, which is part of the drug, GABA-dependent receptors of parasites are blocked, transmission of nerve impulses is disturbed, and as a result, paralysis and death of ectoparasites.
S-methoprene inhibits the function of juvenile hormone, which is involved in the formation of chitin, resulting in impaired development of eggs and larvae of a future flea.
When applied to the skin, absorption of the drug does not occur. The remedy gradually, over the course of a day, is distributed over the surface of the body and, lingering in the sebaceous glands, has a long insecto-acaricidal effect in places where ectoparasites accumulate.
The drug "Frontline" (reviews can be read on the forums) - low-risk tool. If used in recommended doses, the drug does not have a skin-resorptive, embryotoxic, sensitizing, mutagenic and teratogenic effect. If substance gets into eyes, mild irritation may develop.
Indications for use
Apply a remedy to get rid of dogs and cats from fleas, lashing, lice and ticks. “Frontline” is used as follows: break off the tip of the pipette with the medicine, spread the fur in the animal's back area and apply the drug at several points. The volume of the “Frontline Combo” pipette used depends on the type and weight of the animal.
For dogs use the following volumes:
for the weight of 2-10 kg - 0.67 ml,
for the weight of 10-20 kg - 1.34 ml,
for the weight of 20-40 kg - 2.68 ml,
for weight over 40 kg - 4.02 ml.
For cats use 0.5 ml.
The drug protects against the appearance of ticks in cats for 3 weeks, from the imaginal and preimaginal phases of the development of parasites - for 6 weeks. It prevents the occurrence of ixodic ticks in dogs during the month, protects from adult parasites for at least 3 months, and from the pre-imaginal phases of the development of parasites - up to 8 months.
special instructions
The drug "Frontline" in the form of drops can not be used for puppies under the age of eight weeks. In this case, apply the spray "Frontline". After treatment with the agent, it is recommended to walk with a pet in the area of possible attack of ticks only after 24 hours. Within two days after using the drug should not bathe the dog.
If the animal is severely affected by lice, fleas, lice, processing is done once every 4 weeks. If the animal is bathed more than twice a month, the interval between treatments is recommended to be reduced to 3 weeks.
Those who used Frontline for their pets usually give positive feedback:
side effects and complications when using the tool in the recommended doses is not observed,
the drug can be safely used for bitches during pregnancy and lactation,
if the dog is accidentally licked off, the salivation will increase for a short time,
swallowing the drug is also safe, as the drug acts extremely selectively - exclusively on the nervous system of invertebrates.
Security measures
During the work with the preparation "Frontline" it is necessary to follow certain rules of safety precautions and personal hygiene:
wash your hands thoroughly with soap and water,
during the next minimum of 12 hours, do not contact with other animals and children,
eating, drinking, smoking is prohibited while working with medicine,
in case of accidental contact with the open areas of the skin or mucous membranes, it is necessary to immediately wash it off under running water,
after completing the work, wash your hands thoroughly in warm water and soap;
In no case should empty pipettes be used for domestic purposes, they must be disposed of.
In a short time and for a long period, Frontline will help relieve your pet of various parasites. Reviews of the tool indicate its speed and effectiveness. However, before using the medication, consult your veterinarian.
Release form and composition of the drug frontline spray for dogs
Frontline is available in the form of spray and drops. The volume of clear liquid is 100 ml and 250 ml. It is packed up in plastic bottles with a spray.
Frontline 100 ml is suitable for handling small breeds of dogs and cats.
Frontline 250 ml is designed for use on dogs of breeds of medium and large sizes.
One bottle of funds is enough to handle one animal for an average of 1 year.
The active active ingredient is fipronil.
The effect occurs immediately after drying of the wool, after processing
Indications for use and mechanism of action
Frontline is indicated for treating cats and dogs against lice, fleas, ixodid ticks, cheyletyellas and lashes.
It is prescribed for the prevention of infection and treatment of diseases caused by infection with ectoparasites.
Getting on the animal's hair when spraying the spray, the active ingredient of the drug penetrates into the sebaceous glands, wool and epidermis and is there for a long time. Precisely because of this, the effect of the funds is maintained regardless of how much the pet is being bathed.
The mechanism of action of the drug is based on the blocking of parasite receptors and impaired transmission of nerve impulses. These processes lead to the paralysis of the death of insects.
From ticks protects 1 month, from fleas - 2 months.
Instructions for use
Treat animal recommended in fresh air. If it is necessary to spray the frontline indoors, then it must be thoroughly aired during and after the use of the drug.
Do not allow the drug to enter the mucous membranes of the eyes, mouth, nose
To apply the pet's coat, you must carefully shake the contents of the bottle. Then, at a distance of 15 cm from the wool, spray on the entire surface of the animal's coat, not forgetting the ears and skin folds.
If the pet is long-haired - you need to push the hairs, so that the liquid falls on the skin. After spraying means, you need to massage the body of a dog or cat, for better distribution of the spray.
Frontline dosage for one animal is approximately equal to 5 ml per 1 kg of weight. It is possible to determine the amount of funds based on the number of injections In one press of a spray bottle, about 0.5 ml of liquid is sprayed from a 100 ml bottle, from a bottle of 250 ml - 1.5 ml.
Special recommendations
- Treat your pet with rubber gloves.
- After spraying means thoroughly air the room.
- For two days after applying the product to the animal's hair, do not touch the four-legged friend or iron it.
- Ensure that the animal does not lick the frontline from the body.
- Two days before and after treatment, do not bathe the pet.
- After using the spray, thoroughly wash the pet bedding to prevent re-infection.
Side effects
Side effects when using the drug were not identified.
If you exceed the recommended dosage of more than three times possible increased salivation, vomiting and tremor.
Local allergic reactions are possible. When they are detected, it is necessary to wash off, give the pet an antihistamine drug. Next, the spray must be replaced with another anti-parasitic drug, to prevent the manifestation of re-allergies.
In the event of side effects, it is necessary to thoroughly wash the solution from the dog's woolen and skin integuments and to prescribe symptomatic treatment (absorbents and antihistamines).
Price and analogues
The cost of a spray for 100 ml is 1000 rubles, for 250 ml - 1600 rubles.
Analogs: Beafar, Adventis drops, Leopard, Bolfo, Ultra Guard drops, etc.
Beaphar (Beafar Top 10) TOP 10
In the article, I talked about the frontline spray. Explained for what is used and how it works, what it consists of and in what form it is produced. She described how the dosage is calculated and the drug is used, which are contraindications and side effects. Brought the price of the spray, analogues, shelf life and storage conditions.
What is frontline
In 1997, the veterinary companies Merck & Co and Sanofi-Aventis formed a subsidiary of Merial. In January 2017, the German company acquired this branch and began to actively engage in the development of modern veterinary drugs.
It is interesting! The company introduced the Frontline line of innovative insecticide-acaricidal preparations to the market. The active ingredient is fipronil, which acts on the nervous system of the parasite and neutralizes it.
Frontline is also able to act on pests even at the stage of eggs and larvae, destroying their chitinous shell.. For the animal itself, the drug is safe, as it does not penetrate into the blood, but only accumulates in the sebaceous glands.
Frontline release forms
There are five forms of drug release:
- Frontline spray (Active substance: fipronil) - indispensable for the fight against fleas and ticks. Suitable for puppies from two days of age, as well as adult dogs. Very convenient for dosing. Available in volumes of 100 and 250 ml. The effect occurs immediately after drying of the wool, after treatment.
- Spot he (Active substance: fipronil) - it is used against lashing, fleas, lice, ticks (ixodic and scabies), mosquitoes. Available in droplets in tubes. Volumes vary depending on the weight of the pet: S, M, L, XL.
- Combo (Active substance: fipronil and S-methoprene) - aimed at combating adult parasites, and the larvae and eggs of fleas, ticks, lice, lice. It guarantees the elimination of all harmful insects that are present on the body of the dog within 24 hours. At repeated use protection against insects within a month is guaranteed. Available in the form of drops on the withers, the volumes of S, M, L, XL.
- Three-act (Active substance: fipronil and permethrin) - is aimed at the destruction of fleas, ticks, lice, eaters, flying insects: mosquitoes, mosquitoes, flies-flies. It has a repellent effect. Form release: five types of pipettes 0.5 ml., 1 ml., 2 ml., 3 ml., 4 ml, 6 ml, depending on the weight of the dog. At the rate of 0.1 ml. on 1 kg.
- Nexgard (Active substance: afoxolaner) - used to fight fleas and ticks. Available as chewable tablets. Action occurs 30 minutes after chewing. After 6 hours, all the fleas on the dog's body are destroyed, and after 24 hours, all ticks. Protection is guaranteed for a month. Tablets for dogs are produced with the taste of beef, in various dosages for animals weighing from 2 to 50 kg.
Assignment rules
The drug is prescribed to destroy skin parasites in dogs and cats, such as fleas, lice, ticks. The dosage depends on the weight of the animal.
Important! Weight from 2 to 10 kg - 0.67 ml. 10-20 kg - 1.34 ml, 20-40 kg - 2.68 ml. more than 40 kg - 4.02 ml.
In addition, Frontline is applicable when infected with an ear mite. 4 drops are buried in each ear canal. It does not matter what kind of ear is affected, they are buried in both. To distribute the drug evenly, the auricle is folded in half and massaged.
Contraindications
This drug manifests itself safely against even pregnant and lactating dogs. Acts exclusively on the nervous system of parasites. In cases of accidental ingestion of the drug in the mouth, the salivation in the dogs increased for a while, then the reaction disappeared, without leading to further consequences.
However, you should pay attention to the following instructions:
- Strictly you can not use Frontline in the form of drops for puppies up to two months. It is permissible to treat with the frontline tool in the form of a spray.
- Cannot be used for dogs weighing less than two kg.
- Unacceptable for animals with intolerance to individual components of the drug.
Precautionary measures
As mentioned above, the drug is among the low-risk drugs for the body of dogs. Complies with GOST 12.1.007.76. However, when working with Frontline, as with any drug, you should take precautions:
- Clearly comply with the dosage of the drug.
- Do not use with anti-parasitic collar.
- Observe age restrictions on the use of funds.
- Use with caution in impaired and aged dogs.
- Use with caution for pregnant and lactating individuals. If possible, during these periods, avoid any chemical exposure without special indications.
- Be sure to check with the veterinarian for possible reactions of interaction of fipronil with other drugs.
- Before use, you must make sure that the dog does not have individual intolerance to the components of Front Line.
Frontline cost for dogs
The price of Front Line products depends on the form of release and dosage. Prices are at the time of 2018, in Moscow.
- Frontline in the form of drops for dogs costs an average of 400 to 800 rubles.
- Drops Spot-On from 420 to 750 rubles.
- Drops Three-act from 435 to 600 rubles.
- Drops Frontline Combo from 500 to 800 rubles.
- The price of Front Line Spray 100 ml is 1200-1300 rubles in Moscow.
- A 250 ml frontline spray will cost an average of 1,500 rubles.
Important! Any drugs should be bought in specialized veterinary pharmacies. Buying in other places does not guarantee the authenticity of the drug and the safety of its use for the life and health of not only the pet, but also the person himself.
In regions, prices fluctuate, the difference is 15-20%.
Frontline reviews
I use Frontline for more than two and a half years, using ticks during the attack. I drip on the withers first and spray a little. Quite a bit. As a result, no ticks! and earlier, five pieces after the walk took off.
A wonderful tool and most importantly, what is convenient, there is a large dosage! Up to 60 kg. I have three bullmastiffs, so it is very convenient and it turns out even cheaper than buying separately and combining, calculating grams.
I am absolutely pleased with the use of Frontline. We discovered it about three years ago. From personal observations: I noticed that the drug, which is produced by France, acts much more efficiently than that produced in Poland. When buying, I always choose France, in the same pharmacy, works with a bang. But an important point! Dog breeders shared that some dogs have Front Line intolerance. It can reach anaphylactic shock and even death.
Important! And you can not use together with the "anti-flea" collars in any case!
Composition, release form
FRONTLINE® Spot It is an insecticoacaricidal preparation containing fipronil as an active substance, as well as excipients and solvents.
Each blister is packed in a cardboard box. Each box is labeled with the name of the manufacturer and its trademark, volume, purpose and composition of the drug, batch number, date of manufacture, shelf life.
Order of use and dosage
Before use, the tip of the pipette is broken off, the hair is pulled apart at the withers (between the shoulder blades) and pressing the pipette, the contents are completely squeezed onto the skin in one or several points.
After applying the drug itself spreads throughout the skin of the animal within 24 hours. Depending on the type and weight of the animal, FRONTLINE® Spot pipettes are used. It is of various sizes:
Order of use and dosage
The preparation FRONTLAYN® Spot It is used to treat otodektoz (ear scabies). For this purpose, they are instilled into each ear for 4-6 drops (drops must be injected into both ears).
For even distribution of the drug, the auricle is folded in half and lightly massaged its base, the residue applied on the skin between the shoulder blades (single treatment).
Pharmacological properties
Фипронил, входящий в состав препарата блокирует рецепторы гамма-амино-маслянной кислоты нервных клеток паразита и обладает выраженным инсектицидным и акарицидным действием в отношении вшей, блох, власоедов и клещей (иксодовые, хейлителлы, отодектосы), паразитирующих на собаках и кошках. В результате нервного перевозбуждения паразит быстро умирает.
Депанация препарата в сальных железах создаёт «эффект резервуара» и обуславливает длительность его воздействия и водоустойчивость.
ФРОНТЛАЙН® Спот Он в течение 24 часов постепенно распределяется по всей поверхности тела и обеспечивает защиту животных от эктопаразитов. Продолжительность защиты животных от клещей: у кошек 3 недели, у собак 1 месяц.
Duration of protection of animals from fleas: in cats - 2 months, in dogs 3 months.
Repeated treatment of animals is carried out after the specified time.
FRONTLINE® Spot It, according to the degree of its impact on the body, belongs to the group of low-hazard substances - according to GOST 12.1.007.76 it does not have a skin-resorptive, sensitizing, embryotoxic, teratogenic and mutagenic action.
Eye contact causes mild irritation.
Frequently asked Questions
Is Frontline® Spot Safe for pregnant and lactating animals?
FRONTLINE® Spot. It has passed numerous laboratory tests. It does not have any side effects on pregnant and lactating dogs and cats. It is the only drug recommended for the treatment of lactating and pregnant dogs and cats.
If my pet starts licking itself after treatment, is it dangerous? Apply FRONTLINE® Spot It in places where the animal cannot lick it off.
If the drug is swallowed, short-term hypersalivation may occur (increased salivation). It is safe to swallow and does not cause intoxication, as it acts selectively on the nervous system of invertebrates.
How fast will FRONTAINE® Spot He kill the fleas on my pet? FRONTLINE® Spot It kills 98-100% of fleas in less than 24 hours before the flea lays eggs.
How often to re-process the animal? It is recommended to treat the animal with FRONTLINE® Spot. It against fleas: every 2 months for cats and every 3 months for dogs. In the case of treatment and prevention of allergic flea dermatitis or the risk of tick infestation once a month.
Does FRONTLINE® Spot scare off ticks and does it warn tick bites? No, Frontline® Spot It is not a repellent. It acts in such a way that the tick could not transmit dangerous diseases.
Ticks, on average, require at least 48 - 72 hours to transmit pathogenic agents. During this time, Frontline Spot. It minimizes the risk of transmission of tick-borne diseases (piroplasmosis, Lyme disease, etc.)
How to use FRONTLINE® Spot It for animals with a border weight or weight over 60 kg? In the case of borderline weight, use the pipette in the direction of weight gain, for dogs weighing more than 60 kg. A combination of 2 types of pipettes should be used: maximum weight + additional pipette with missing weight.
Do I need to use other means against ectoparasites?. FRONTLINE Spot It is so effective that it does not require the use of additional means of protection and there is no need to combine it with other drugs.
Remember - the safety of external anti-parasitic drugs varies from case to case.
Frontline for dogs: types of drugs and instructions for use
The drug Frontline for dogs and puppies produces the company Merial (France). It is used to combat head lice, lashing, fleas and various types of ticks.
It is applied to the skin in the form of drops or spray. It is an insecticoacaricidal drug whose active ingredient is fipronil, as well as solvents and auxiliary substances. Fipronil blocks the nerve cells of a parasite that dies as a result of nervous overexcitation.
The Frontline Combo for Dogs also has S-Methoprene. His task is to destroy the chitinous shell of a flea at the stage of an egg and a larva. The drug does not penetrate into the blood, but only accumulates in the sebaceous glands and the epidermis of the animal, this ensures the duration of the Frontline effect.
Forms of release of a drug and dosage
The most commonly used form of Frontline and its variations of Frontline Combo is a polyethylene pipette with a breakable tip. These pipettes have several dosages designed for animals with different weights: 4.02 ml for more than 40 kg, 2.68 ml for 20-40 kg, 1.34 ml for 10-20 kg and 0.67 ml for weight from 2 up to 10 kg.
On average, it has 200 clicks, and 6-12 clicks are designed for processing 1 kg of animal mass. A larger bottle is designed for dogs weighing 12 kg or more. It has about 160 clicks and 1 kg of animal mass needs 2-4 clicks depending on the length of the coat.
Release form and active substances
Different volumes of vials and pipettes designed for dogs of different sizes, which are described below for instructions for use of the frontline.
Release form
In the Frontline Combo, there is also an additional active ingredient, S-methoprene (designed to fight flea eggs and larvae, destroying their chitinous membrane). Therefore, the drug Frontline Combo is effective against most parasites, regardless of the stage of their development.
Indications and contraindications
Indications for use:
- fleas (disposal prevention),
- ticks (deliverance / prevention),
- other ectoparasites (deliverance / prevention).
- Do not use on puppies younger than 10 weeks old,
- must not be used on dogs weighing less than 2 kg,
- can not be used on sick animals
- can not be used with individual sensitivity to the components of the frontline.
Frontline price for dogs
- Frontline drops for dogs, the price ranges from 580 to 800 rubles (depending on the volume),
- For flea drops for dogs, the frontline combo price ranges from 700 to 980 rubles (depending on the volume),
- for Frontline Spray for Dogs the price is about 1280 rubles for a bottle of 100 ml, about 2090 rubles for a bottle of 250 ml.
You can buy Frontline for dogs at any veterinary pharmacy, but if for some reason you are not satisfied with your dog or do not suit your dog, you can use the following analogues for fleas:
- Drops Advantiks from fleas for dogs (the price is about 440 rubles),
- Drops the Leopard from fleas for dogs (the price is 160-230 rub),
- Drops Beafar from fleas for dogs (price 135-200 rubles),
FRONTLINE Spot It (Frontline Spot On)
COMPOSITION AND FORM OF ISSUE. Frontline Spot It contains fipronil (chemical formula: C12H4CL2F6N4OS) in 10% concentration as an active substance, as well as auxiliary substances and solvents.
PHARMACOLOGICAL PROPERTIES. Fipronil has a pronounced contact insect-acaricidal effect on ectoparasites of dogs: lice, fleas, lashes, ixodid ticks, as well as cheyletiella and earwax pathogen.
The mechanism of action of fipronil is to block the GABA-dependent receptors of the parasite, in violation of the transmission of nerve impulses, which ultimately leads to paralysis and death of the parasites. Fipronil has no effect on mammalian GABA receptors.
When applied to the skin of an animal, the drug is practically not absorbed and during the day is evenly distributed over the surface of the body, accumulating in the sebaceous glands of the skin, providing a prolonged insect-acaricidal effect.
INDICATIONS. Assign cats and dogs against ectoparasites: fleas, lice, lashing, ixodid ticks, cheyletyell. For the treatment of otodektoz (ear scabies) in animals.
DOSES AND METHODS OF APPLICATION. Frontline Spot It is applied externally by topical (spot) application to the skin. Before processing, the tip of the pipette is broken off and the fur in the back area (between the shoulder blades) is moved apart in the animal and, pressing the pipette, completely squeezes its contents onto the skin at one or several points.
Depending on the body weight, pipettes with different amounts of the drug are used to treat animals:
Amount of drug
If the weight of the dog is about 10 kg, then you should use a pipette for dogs from 10 to 20 kg (ie, you need to choose a pipette with a large amount of the drug). If the weight of the animal is more than 60 kg, then two pipettes for dogs from 20 to 40 kg should be used.
The protective effect of the drug against ticks is 1 month (for cats 15-21 days), against insects - 2-2.5 months (for cats 1.5 months). For the treatment of otodecosis (ear scabies), the ear canal is cleaned of crusts and scabs and the preparation is instilled into both ears for 4-6 drops, even if only one ear is affected.
In advanced cases otodektoz complicated by otitis, antibacterial and anti-inflammatory drugs are prescribed. The drug can be used in pregnant and lactating females. Wash animals with shampoo no earlier than 48 hours after treatment.
SIDE EFFECTS. In hypersensitive animals, allergic reactions are possible. In these cases, the use of the drug is stopped, the remnants of the drug on the skin are removed with a cotton swab and washed with water, if necessary, conduct desensitization therapy.
CONTRAINDICATIONS. Increased individual sensitivity to the components of the drug. Puppies and kittens younger than 8 weeks of age cannot be processed.
SPECIAL INSTRUCTIONS. When carrying out manipulations with the drug, it is recommended to use rubber gloves, especially if there are abrasions on the hands and other skin lesions. During processing it is forbidden to drink, smoke and eat.
You should not pet the animal and allow it to reach small children within 24 hours after applying the drug. In case of accidental ingestion of the product on the skin or mucous membranes, it must immediately be washed with a stream of water or removed with a swab and then washed with water. At the end of the treatment, hands should be washed thoroughly with warm water and soap.
STORAGE CONDITIONS. With precaution. In the manufacturer's packaging, in a dry, dark place and out of reach of children and animals. Separated from food and feed at a temperature of from 0 to 35 ° C. Shelf life - 3 years.
MANUFACTURER. Merial S.A.S. (Merial S.A.S.), France.
Manufacturer
Front Line is one of the products of Merial, a company specializing in the development and manufacture of vaccines and veterinary products for livestock and for pets.
Now they are one of the world leaders in the field of veterinary medicine, and are actively engaged in research activities, as well as the creation of innovative products in the field of animal health.
Frontline spray
It is used to fight ticks and fleas in adult dogs and puppies from two days old. The active ingredient here is fipronil, which has a detrimental effect on ectoparasites. The spray has several advantages over other forms of the drug: it is convenient to dose it, you can use it for pets weighing less than 2 kg, the protective effect occurs immediately after drying the treated wool. It is produced in bottles of 100 and 250 ml.
The classic product containing fipronil, in the form of drops for application to the skin. It is used against fleas, lashing, lice, ixodic and scabby mites, mosquitoes. Available in blue tubes, sealed in blisters. The volume of Frontline Spot-It is divided into four varieties, depending on the weight of the pet:
Pipette volume and package designation
Drops on the withers, like Spot-on. It differs from the previous one in that it contains the second active substance (S) -methoprene, which in addition kills eggs and flea larvae. This tool is available in green pipettes and packaged also in four types of packages, depending on the dog's weight: S, M, L, XL.
The solution, which is also applied to the withers. Their main difference is the active protection not only from fleas and ticks, but also from flying insects: mosquitoes, mosquitoes, flies. In addition to fipronil, the formula includes permethrin, one of the properties of which is repellent (insect repellent). Available in five types of pink pipettes designed for different dog weights: 0.5, 1, 2, 4 and 6 ml, at the rate of 0.1 ml of the preparation per 1 kg of pet's weight.
The drug in the form of chewable tablets, which is designed to rid the pet of fleas and ticks. To the dog ate it itself, the tablet has an attractive taste of beef stew. The main active ingredient in it is afoxolaner, it begins to act almost immediately - 30 minutes after eating. After 6 hours, all fleas are completely destroyed, and after a day, all ticks. The protective effect lasts one month. Chewable tablets come in four types of dosages: 0.5, 1.25, 3, and 6 grams, for dogs weighing from 2 to 50 kg.
Description and effect of the drug
One of the most well-known medicines in this series is drops on the withers for Frontline Combo dogs.
It is based on two active ingredients - fipronil and (S) -methoprene. Fipronil acts on adult parasites, causing paralysis in contact with them, which leads to their subsequent death. A (S) -methoprene affects the eggs and larvae of insects, thereby interrupting the cycle of their development, and hence the risk of re-invasion. Plus, this feature will help protect the dwelling itself, because the reproduction of these parasites and further infection of the dog’s habitat stops completely.
All drops for Frontline dogs have the same principle of action, so the instructions for them are almost identical. Immediately after contact with the skin of the animal, the substance begins to be distributed and gradually cover the entire skin and coat. This process is completed within 24 hours. The drug does not enter the bloodstream, but accumulates in the outer layer of the skin, hair follicles and sebaceous glands, creating a protective barrier. This kind of shield protects the dog from ticks for four weeks, and from fleas - 4-12 weeks. The duration of the protective effect can be affected only by frequent bathing of the pet with shampoo (more than 2 times a month).
Range
To date, there is a whole range of tools aimed at protecting the animal from fleas and ticks, produced under the brand name Frontline.
Frontline spray. It is used to fight ticks and fleas in adult dogs and puppies from two days old. The active ingredient here is fipronil, which has a detrimental effect on ectoparasites.
Spot he. The classic product containing fipronil, in the form of drops for application to the skin. It is used against fleas, lashing, lice, ixodic and scabby mites, mosquitoes.
Available in blue tubes, sealed in blisters. The volume of Frontline Spot-It is divided into four varieties, depending on the weight of the pet:
By volume Frontline Spot-It is divided into four varieties.
Combo. Drops on the withers, like Spot-on. It differs from the previous one in that it contains the second active substance (S) -methoprene, which in addition kills eggs and flea larvae. This tool is available in green pipettes and packaged also in four types of packages, depending on the dog's weight: S, M, L, XL.
Three-Act. The solution, which is also applied to the withers. Their main difference is the active protection not only from fleas and ticks, but also from flying insects: mosquitoes, mosquitoes, flies.
In addition to fipronil, the formula includes permethrin, one of the properties of which is repellent (insect repellent). Available in five types of pink pipettes designed for different dog weights: 0.5, 1, 2, 4 and 6 ml, at the rate of 0.1 ml of the preparation per 1 kg of pet's weight.
Nexgard. The drug in the form of chewable tablets, which is designed to rid the pet of fleas and ticks. To the dog ate it itself, the tablet has an attractive taste of beef stew.
The main active ingredient in it is afoxolaner, it begins to act almost immediately - 30 minutes after eating. After 6 hours, all fleas are completely destroyed, and after a day, all ticks.
The protective effect lasts one month. Chewable tablets come in four types of dosages: 0.5, 1.25, 3, and 6 grams, for dogs weighing from 2 to 50 kg.
Frontline Combo (Front Line Combo) XL drops for dogs from 40 kg
Frontline Combo (Frontline Combo) - medicinal insecticide acaricidal drug in the form of a solution for external use.
Frontline Combo contains fipronil-9.8% as active substance and S-methoprene, 8.8%, and polyvidone and polysorbate as auxiliary substances.
They produce Frontline Combo packaged in 0.5, 0.67, 1.34, 2.68, and 4.02 ml polyethylene pipettes with a breakable tip, which indicate the name of the manufacturing organization, the name and quantity of the medicinal product, the series number, date manufacturing.
Store Frontline Combo with caution (List B) in the manufacturer's packaging, in a dry, dark place at temperatures from 0С0 до 25С0.
The shelf life of Front Line Combo, subject to the storage conditions - 3 years from the date of manufacture. Frontline Combo should not be used beyond the expiration date.
Vaccine use order
Frontline Combo is used to fight fleas, lice, jaws and ticks (ixodic, cheilitella) dogs and cats by topical (Spot It) application to the skin.
For processing dogs weighing more than 40 kg, use a combination of pipettes of different sizes.
The protective effect of the drug against ticks in cats lasts up to 3 weeks, against adults and preimaginal phases of insect development up to 6 weeks.
The protective effect of the drug against ixodic ticks in dogs lasts at least 1 month, against imago insects up to 3 months, from the preimaginal phases of insect development to 8 months.
With a strong defeat of the animal with lice, fleas, lashes, it is recommended to perform treatment once a month.
If the animal is washed more often 2 times a month, it is recommended to reduce the interval between treatments to 3 weeks.
It is not recommended to wash animals for 48 hours after processing by Front Line Combo, as well as to use other insecticoacaricidal agents.
Side effects and complications in animals when using Frontline Combo according to the instructions for use is not installed. При повышенной индивидуальной чувствительности к компонентам препарата и появления признаков аллергических реакций обработку прекращают, препарат смывают водой, внутрь дают антигистаминные средства.
Не подлежат обработке больные и выздоравливающие животные, а также щенки и котята моложе 8-недельного возраста.
Побочные действия: В рекомендуемых дозах не отмечаются.
MERIAL FrontLine Spot On S (Фронтлайн) капли для собак весом от 2 до 10 кг
Показания: Профилактика и борьба с эктопаразитами собак и кошек (блохи и клещи). Продолжительность защиты от повторных инвазий:
- for dogs: two months from fleas and one month from ticks,
- for cats protection against fleas for 40 days.
Side effects. In the case of licking, temporary hypersalivation may occur.
Ingredients: Fipronil 10g, Butylhydroxyanisol 0.02g, Butylhydroxytoluene 0.01, Ethanol 10ml, Excipient up to 100ml
Duration of protection against repeated invasions: two months from fleas and one month from ticks.
Packaging: 3 types of packaging for dogs, 1 type of packaging for cats:
- in a pipette of 2,68 ml for dogs of 20-40 kg
- in a pipette of 1,74 ml for dogs of 10-20 kg
- in a pipette of 0,67 ml for dogs of 2-10 kg
- in a pipette of 0,55 ml for cats
Application: One Frontline pipette is designed for one-time processing based on the weight of the animal.
Break off the tip of the pipette at the designated location. Apply the contents directly on the skin at the withers (between the shoulder blades), after spreading the fur apart, to avoid licking.
In less than 24 hours, the drug itself naturally spreads over the entire surface of your animal's body. Avoid getting the product on your hands. In the case of licking, temporary hypersalivation may occur.
Recommendations: Do not bathe the animal for two days before, and after applying the frontline drug.
As with all insecticides:
- wash your hands with soap after applying
- during the use of the drug is not allowed to smoke, drink and use food,
- Keep the drug out of the reach of children.
Contraindications: Not identified. It is not recommended to handle puppies up to 10 weeks of age or weighing less than 2 kg.
Storage: In the dark, dry place at a temperature of from 0 to 50 ° C.
