Veterinary medicine

Instructions for use of the drug milprazon for dogs


Every owner knows how dangerous a helminth infection can be for a cat. Parasites can disrupt the metabolism of a pet, harm its immune system and even destroy the integrity of internal organs.

To avoid this, it is necessary to have in the first-aid kit a reliable preparation that will help to cope with the worms and will not have a detrimental effect on the pet's body. One of the best on the recommendations of veterinarians is "Milprazon" for cats. Reviews about him say about the effectiveness and rapid action of the drug without harm to the animal.

Composition and release form

The drug belongs to the category of anthelmintic drugs intended for oral use. Instructions for use "Milprazon" for cats contains information that the main active ingredient of the drug is praziquantel, as well as milbemycin oxime. The drug is available in two forms:

  • For cats up to 2 kg and kittens. The medicine consists of milbemycin oxime at a dosage of 4 mg and praziquantel at 10 mg. Form release - pills yellow.
  • For cats more than 2 kg. It can also be given to dogs. Each tablet contains 14 mg of milbemycin oxime and 40 mg of praziquantel. Color tablets - brown with a reddish tinge.

As an adjunct, the medicine contains meat flavor, microcrystalline cellulose, povidone, silicon, lactose, and magnesium stearate. The tablets themselves have a biconvex shape and are coated. Sold in blister packs of 2 and 4 pieces.

When is the drug prescribed?

Based on the instructions for use, as well as numerous reviews, "Milprazon" for cats is prescribed when establishing one of the following diagnoses:

  • Associative invasion of mixed type.
  • Nematodosis
  • Cestodiasis

In addition to the obvious infection with parasites, Milprazon can be given to an animal as a prevention of helminths, as well as to prevent the appearance of dirofilariasis.

Drug action

Reviews of "Milprazon" for cats say about the amazing effectiveness of the drug. It is explained by the presence of two active ingredients in the composition. It is they who, when they enter the blood of an animal, damage the nervous system and tissues of the parasites. In addition, the development of larvae, which have been shelved for breeding, stops. All individuals, regardless of the life cycle and size, die. The remnants of their vital activity are excreted from the body of the cat along with feces.

The drug is a potent agent. Therefore, it should be given to the animal with extreme care so as not to harm the health of the pet. You should always carefully read the instructions for the use of "Milprazon" for cats. Reviews of pet owners say that you need to give a tablet strictly based on the weight of the pet.

Instructions for use

For the treatment and prevention of helminths, the drug is given once, dissolving the tablet in a small amount of water or mixing with food. If the pet refuses to use disguised medicine, you need to feed it forcibly. In this case, you need to put a pill under the root of the cat's tongue and wait until it swallows it. For treatment, the drug is given only after the appointment of a veterinarian. As a preventive measure, the pill must be given every 4 months. The dosage of the drug depends on the weight of the pet. "Milprazon" for cats up to 2 kg should be given as follows:

  • Kitten from 500 g to 1 kg need to feed half a tablet.
  • For a weight of 1 kg or more, you need a whole tablet.

The release form of the medicine for cats from 2 kg assumes the dosage:

  • From 2 to 4 kg - half a tablet.
  • From 4 to 8 kg - the whole tablet.
  • From 8 to 12 kg - one and a half tablets.

The instructions for use also contain information that it is prohibited to give medicine to pregnant and lactating animals without a veterinarian’s approval. Reviews of "Milprazon" for cats say that non-compliance with this rule can greatly harm the health of the pet.

Reviews and veterinary advice

Veterinarians speak very positively of this drug. Nevertheless, they advise giving medicine to cats, strictly following the instructions for use. Adult animals usually tolerate the treatment and prevention of worms. But the kittens up to 6 weeks veterinarians advise not to treat parasites. An immature organism cannot cope with such a potent drug.

Reviews of veterinarians about "Milprazon" for cats say that the drug can harm if you give it to a sick pet. Before deworming, doctors advise to make sure that the animal is completely healthy. To do this, it is necessary to measure its temperature, and also to check the general state of health. The cat must be in good spirits, enough sleep, eat and move. The tablet "Milprazon" should not be given on an empty stomach - the pet must eat well.

Precautionary measures

When handling this medication, certain precautions must be observed:

  • Holding a pill in your hands, you should follow the rules of hygiene, as well as safety precautions, which are indicated in the instructions for using the product. Before you take a pill, wash your hands thoroughly with soap and water. The same must be done immediately after the deworming procedure from worms. “Milprazon” for cats is very toxic when ingested. When you come into contact with medicine, you should not eat anything, drink water, smoke or do household chores.
  • If the active substance comes into contact with mucous membranes, immediately rinse the affected areas with running water.
  • Keep "Milprazon" need only in the place that can not find an animal or child. If the drug is ingested, you should immediately call for medical assistance.

Drug reviews

Cat owners also speak well of this drug and prophylactic medication. "Milprazon" always acts effectively and eliminates worms from one time. Many have the convenience of using tablets. Some drugs help only after 2-3 doses. "Milprazon" also acts much faster after consuming 1 tablet. Most pet owners prefer this particular drug to treat and prevent their cats from parasites. It has an acceptable cost, and you can find a medicine at any point in the veterinary pharmacy.

The composition of the drug milprazon and release form

Milprazon is a drug that comes in pill form. Praziquantel and milbemycin act as active ingredients.

There are two dosages:

  1. For little ones dogs (up to 5 kg) and puppies. Oval tablets have a gray-yellow shade, divided in the middle by a deep risk. They contain 25 mg of praziquantel and 2.5 mg of milbemycin.
  2. For pets whose weight exceeds 5 kg. Round tablets of a light yellow shade. They contain 125 mg of praziquantel and 12.5 mg of milbemycin.

Indications for use

Milprazon is used as a preventive and therapeutic purposes for helminth infections in dogs. The components of the drug affect adult tapeworms and roundworms, their larvae and adults. Also, the drug has a detrimental effect on microfilariae (heartworm larvae - dirofilaria).

After ingestion, the active substances are absorbed into the bloodstream and reach a maximum concentration within 1-4 hours. Milbemycin and praziquantel help to increase the permeability of the cell membranes of adult parasites and their larvae. This leads to muscle contraction and subsequent paralysis of the worm, after which it dies.

Excreted from the body in a couple of days with urine. In most cases, it is enough to feed a pill to a pet once, but with a strong worm infestation it is necessary to repeat the administration in 7-10 days.

Instructions and dosage

Milprazon is fed to the dog along with a piece of treat or during the first meal. You can also enter the drug forcibly at the root of the tongue.

The regimen depends on the type of worms parasitic in the body of the animal:

  • When angiostronglosis, the medicine is fed four times with an interval of a week. For the prevention of milprazon give a dog every month.
  • In case of telaziose, the tablets are fed twice with an interval of 7 days.
  • For the prevention of dirofilariasis, milprazon is given to a pet during the season of activity of blood-sucking insects every month.
  • For intestinal helminthiases, the drug is given once or twice (with an interval of 7-10 days), and for prophylaxis it is enough to feed the drug every 3-4 months.

Dosage is calculated by body weight:

Side effects and contraindications

The manifestation of side effects is possible if the drug was given to the dog in excessive dosage. At the same time, the animal has a precarious gait, the general condition is depressed. There may be excessive salivation and tremors in the muscles.

Contraindications include:

  • pet age less than 2 weeks
  • dog weight less than 500 grams,
  • disorders of the liver and kidneys,
  • dogs suffering from infectious diseases.

Cost and analogues

The drug goes on sale in packages, each containing 2 tablets. The cost of milprazon for dogs whose weight is less than 5 kg varies from 250 to 320r., The dosage for animals more than 5 kg has a price of 400-460r.

Milprazon can be replaced by the following analogues:

  • Helmimax. It contains moxidectin and praziquantel as active ingredients. Effective with intestinal worms and dirofilariasis. Available in the form of tablets of various dosages.
  • Dironet. Contains substances such as pyrantel pamoat, ivermectin and praziquantel. It is used for helminthiasis (round and tapeworms), as well as for dirofilariasis. Available in pill and liquid suspension form.
  • Milbemaks. The drug containing milbemycin and praziquantel. Effective with helminthic invasions caused by tape and roundworms, as well as dirofilariasis. Available in the form of small tablets of various dosages.
  • Top dog. Tablets, which include febantel, pyrantel embonat, ivermectin and praziquantel. It is used to treat worms caused by tapeworms and roundworms, as well as for the prevention of dirofilariasis. Available in pill form.

Milprazon is an affordable and effective drug that will protect a dog or cat not only from intestinal, but also from heart worms.

It can be given to pregnant animals and small puppies older than 2 weeks. However, before use, you should make sure that the pet does not have serious liver and kidney diseases.

Operating principle

After taking the pill, it will quickly dissolve in the stomach, the active ingredients are immediately absorbed into the tissues and spread through the body through the bloodstream. Praziquantel is especially effective against adult cystodes and nematodes. The substance increases the permeability of cell membranes, causes contraction of the parasite's musculature and its rapid destruction.

After taking the pill, it will quickly dissolve in the stomach.

Dead worms are excreted naturally. The substance reaches its maximum concentration in 1-4 hours after administration, the effectiveness of the component is maintained for 24 hours.

Milbemtsin oxime quickly destroys the larvae of parasites at all stages of development. It inhibits nerve endings and destroys the cell membrane, causing paralysis and death of the worms. The maximum concentration of a substance in the blood is observed 2-4 hours after taking the pill. Milbemtsina oxime is not concentrated in the tissues, displayed in 24 hours unchanged.

Milprazon belongs to the class of low-toxic drugs with a low degree of danger. At observance of the dosages specified in the instruction, the medicine does not adversely affect the health of the dog.

The drug is prescribed for:

  • cestodes,
  • nematodoses,
  • dirofilariasis
  • mixed invasions of varying intensity.

Contraindications and side effects

The drug has a minimum of contraindications. It can be used to treat pregnant and lactating females, elderly and weak animals.

Contraindications may be:

  • puppy age (up to 2 weeks),
  • individual allergic reaction to the components of the drug.

Overdose may cause diarrhea, nausea, and general depression. Unpleasant symptoms completely disappear in a few days and do not require additional treatment. When tremor of the muscles or cramps take drugs symptomatic therapy.

Storage conditions and price

The shelf life of the tablets is 2 years from the date of manufacture indicated on the package. Keep them away from food, medicine and animal feed. You do not need to put the tablets in the fridge; it is enough to remove them away from the heating devices and protect them from direct sunlight.

The cost of Milprazon varies from 294 to 486 rubles, depending on the packaging.

The drug belongs to low-toxic, but requires compliance with all rules of hygiene. After handling the animal, wash your hands thoroughly with soap and water.

Important. Unclaimed tablets are disposed of according to the rules. They can not be thrown out, the active ingredients are poisonous for fish, bees and other insects.

The price of the drug depends on the point of sale and packaging. In the online pharmacy pills for small breeds can be purchased for 294 rubles per pack. Milprazon for large dogs will cost 486 rubles.

Reviews from dog breeders

Margarita, Tomsk. I have Yorkshire terriers, many preparations for worms do not suit them. Always looking for products designed specifically for small dogs to make it easier to dose. Milprazon is perfect in this sense, pills are easily divided. You do not need to mix them with food, dogs take pills for delicacy and eat without whims. No treatment was required, I use the drug only for prophylaxis.

Many breeders use Milprazon for de-worming small puppies.

Zhanna, Perm. The three-week puppies showed worms. The dog was chosen before childbirth, it was not possible to eradicate parasites. I thought I would have to wait until the babies were at least 2 months old. But it turned out that there are medicines that do not harm even such crumbs. In the vetapteka they picked up Milprazon, told how to give it. She worried about the result, but everything went fine, the puppies did not even have diarrhea. Tummies are not so bloated, appetite is good. They will grow up, we will once again anthelmintic.

Victor, Svetlogorsk. We have a Chinese crested with a very gentle stomach, so most potent anthelmintic are not suitable for it. Sprays also can not be used, there will be a strong irritation on the skin. I was looking for a suitable drug for a long time, I decided to try Milprazon. The pills turned out to be quite effective, the dog eats the prescribed dose itself, did not notice any negative reaction. Took pills already 2 times, we will use them further. It is good that they protect not only from ordinary, but also from heart worms, because there are cases when dogs become infected with them, they are more and more often, I don’t want to risk.

Release form, composition and packaging

Tablets for oral administration (for cats weighing more than 2 kg) film-coated, brown-red, oval, biconvex, with a risk on one side, with taste of meat.

Excipients: microcrystalline cellulose - 20.80 mg, lactose monohydrate - 41.5 mg, povidone - 3 mg, croscarmellose sodium - 7 mg, colloidal anhydrous silicon - 1.2 mg, magnesium stearate - 2.5 mg, white opadry - 3.2 mg, meat flavoring (Aroma meat flavor 10022 ) - 0.4 mg, dry yeast - 0.2 mg, iron red oxide (E172) - 0.2 mg.

About 2, 4 pieces are packaged. in the blisters packed into cardboard boxes complete with the application instruction.

Registration certificate 705-3-9.14-2362 No. PVI-3-9.14 / 04384 dated 10.22.14

Pharmacological (biological) properties and effects

Combined anthelmintic drug nematocidal and cestocidal action.

Included in the preparation of the active ingredients provide a wide range of anthelmintic action.

Milbemycin Oxime - macrocyclic lactone, resulting from the enzymatic activity of Streptomyces hygroscopicus var. Aureolacrimosus, active against larvae and imago nematodes parasitizing cats in the gastrointestinal tract, as well as nematode larvae Dirofilaria immitis.

The mechanism of action of milbemycin is due to increased permeability of cell membranes for chlorine ions (Сl -), which leads to overpolarization of the cell membranes of the nervous and muscular tissue, paralysis and death of the parasite. After oral administration of the drug, the maximum concentration of milbemycin oxime in the blood plasma of cats is reached after 2 hours, the compound is excreted from the body mostly unchanged, the half-life is about 13 hours.

Praziquantel is an acylated pyrazinisoquinoline derivative, has a pronounced effect against cestodes and nematodes. Повышая проницаемость клеточных мембран паразита для ионов кальция (Са 2+ ), вызывает деполяризацию мембран, сокращение мускулатуры и разрушение тегумента, что приводит к гибели паразита и способствует его выведению из организма животного.After oral administration of the drug, the maximum concentration of praziquantel in the blood plasma of cats is reached after 1 hour, the compound is excreted from the body mainly as inactive metabolites in the urine, the half-life is about 3 hours.

Milprazon ® tablets for cats according to the degree of impact on the body are moderately hazardous substances (hazard class 3 according to GOST 12.1.007-76), in recommended doses they do not have sensitizing, embryotoxic and teratogenic effects, are well tolerated by cats of different breeds and ages. The drug is toxic to bees, as well as fish and other aquatic organisms.